As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Karen Coleman studies the behavioral, social, and environmental determinants of success after weight loss surgery. An additional focus of her research is on interventions in primary care settings for adult depression. Dr. Coleman’s main areas of interest are health equity and the study of factors at the level of the patient, the provider, and the system that lead to successful interventions for physical and emotional wellness.
Dr. Coleman directs one of the largest weight loss registries ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation with MS. However, new research from Kaiser Permanente ...
For years, researchers have known that many people struggle to lose the weight they gain during pregnancy. Up to 1 in 4 individuals retain at least 10 pounds 1 to 2 years after giving birth, and this lingering weight can raise their long‑term risk of hypertension, cardiovascular disease, and other metabolic problems. Despite the importance ...
Wildfire smoke has increasingly been recognized as a serious public health threat. Now, 2 new Kaiser Permanente studies in Southern California have examined how health risks for both young and old people might be associated with exposure. One study showed that long-term exposure increased the risk of death among older adults, while another found that ...
On a rainy New Year’s morning in Pasadena, Dr. Hui Zhou, a research scientist with the Department of Research & Evaluation, walked alongside Kaiser Permanente’s float, “A Better Idea for Health Care,” in the Rose Parade. It was a moment of pride and joy. Dr. Zhou wasn’t just proud to represent Kaiser Permanente. … ...
For many people, public parks are just a beautiful green space they drive by on their way to work. However, research has shown that parks play a crucial role in people’s physical activity, and the community’s health. By studying parks, researchers aim to understand how these public spaces enhance community health, encourage active lifestyles, and ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.