About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Michael Girvigian headshot
Michael R. Girvigian, MD
Principal Investigator
Los Angeles
Radiation Oncology
Clinical.Trials@kp.org

Dr. Michael Girvigian is a radiation oncologist, assistant chief of the Department of Radiation Oncology, and co-director of the image-guided radiosurgery program for the Kaiser Permanente Los Angeles Medical Center and the Southern California Permanente Medical Group. His clinical focus is on the management of benign and malignant tumors of the brain and spine with the use of image-guided radiosurgery and radiotherapy. He also introduced the use of stereotactic body radiotherapy in the organization ...

Featured Video

Research showing value of exercise before COVID-19 diagnosis earns special recognition

Being active can lower your risk of getting seriously ill with COVID, regardless of your race or the chronic conditions you may have, according to research published last year in the American Journal of Preventive Medicine.

The Kaiser Permanente Southern California findings were important, impactful, and influential. As a result, the journal editors chose the research article, “Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups,” as the American Journal of Preventive Medicine 2023 Article of the Year.

News

Featured Image of News Story Titled: RSV vaccine protects older adults against severe illness

RSV vaccine protects older adults against severe illness

A new study by Kaiser Permanente has shown that the ABRYSVO respiratory syncytial virus vaccine is very effective in reducing emergency room visits and hospital stays due to RSV among older adults. “This Kaiser Permanente research demonstrated the real-world effectiveness of RSV vaccination among those 60 and over,” said lead author Sara Y. Tartof, PhD, ...

Study finds air pollution may increase risk of preterm birth

Exposure to a specific kind of air pollution, fine particulate matter, during pregnancy may significantly increase the risk of spontaneous preterm birth, which can be dangerous for both the mother and the baby, according to a Kaiser Permanente study published in JAMA Network Open. “Consistent with other study findings, this current study has demonstrated that ...

5 questions for … Dr. Javed Sheikh

Javed Sheikh, MD, was recently named 2024 Physician Researcher of the Year by the Southern California Permanente Medical Group. Dr. Sheikh is the vice area research chair for the Los Angeles area on the Regional Research Committee. He is chief of the Department of Allergy and Immunology at the Kaiser Permanente Los Angeles Medical Center ...

Kaiser Permanente’s vaccine side-effect monitor bolsters safety

After COVID-19 vaccines became available in December 2020, several smartphone-based reporting systems were developed to monitor vaccine side effects. They included V-safe from the Centers for Disease Control and Prevention. However, like most large surveillance systems, they had imperfections. Kaiser Permanente Southern California collaborated with the CDC and others to create a new system in ...

No link between COVID-19 vaccines and cardiac-related death

Research conducted at Kaiser Permanente has provided reassurance to the public and lawmakers by refuting claims that COVID-19 vaccines may increase the risk of cardiac-related death. “Our work reaffirms the previously established safety of COVID-19 vaccines,” said lead author Stanley Xu, PhD, of the Kaiser Permanente Southern California Department of Research & Evaluation. The study addressed ...

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Featured Division

Clinical Trials Research

Our physician investigators conduct clinical trials in communities across Southern California, from Bakersfield to San Diego.

The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.

The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.