As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Amandeep Sahota is physician in charge for the Department of Hepatology at the Kaiser Permanente Los Angeles Medical Center. She is also assistant medical director of Transplant Services for Kaiser Permanente Southern California. In this role, she promotes clinical quality programs, implementation of virtual medicine, and data analytics on chronic diseases outcomes. Her efforts have improved patient access to care, advanced screening for advanced liver disease, and innovated care delivery ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
The updated national colorectal cancer screening guidelines that recommend screening begin at age 45 — rather than 50 — can benefit younger adults, a new Kaiser Permanente study found. The study was published October 22, 2024, in Annals of Internal Medicine. It included 267,732 Kaiser Permanente members in Northern California, Washington, and Colorado ages 45 ...
Breast cancer survivors commonly continue to use opioid pain killers after their cancer treatment is complete. A new Kaiser Permanente study shows that this can increase their risk of falls and bone fractures, lung problems, and cardiovascular conditions. The study was published in October 2024 in The Oncologist. A cancer epidemiologist partnered with a breast ...
Heidi Brown, MD, MAS, is a urogynecologist and a dissemination and implementation scientist who joined the Department of Research & Evaluation in August 2023. Her research focuses on improving access to effective solutions for pelvic floor disorders such as bladder and bowel incontinence and pelvic organ prolapse. She uses community engagement, user-centered design, and iterative ...
Monitoring of about 45,000 pregnant people receiving flu vaccines in each of 2 successive pregnancies showed no increased risk of side effects or health issues, according to a Kaiser Permanente study published September 19, 2024, in JAMA Network Open. “Our study’s findings support recommendations to give flu vaccinations to pregnant persons even if they received ...
A Kaiser Permanente Southern California study showed that 1 heart-failure medication worked best among the 3 most commonly used to prevent illness and disease among patients with chronic kidney disease and heart failure. “Beta blockers save lives in heart failure patients, but we wanted to see how this worked among patients who also had chronic ...
In our newest edition of IMPACT, we share stories of 2 recently released studies about flu vaccines. One looks at which vaccines are best for seniors, while the other assesses the safety of flu vaccines for women with closely spaced pregnancies. Another article examines research that found that gay men had shorter age-adjusted telomere length, which is a biomarker of aging, than straight men. Read also about research showing that beta blockers aren’t all the same for patients with heart failure and chronic kidney disease. The Q&A is with a researcher and physician who specializes in an often under-discussed issue: pelvic floor disorders. We wrap up with links to recent news articles on our research, including one in the New York Times.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.