About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. Joan Ryoo headshot
Joan J. Ryoo, MD, MSHS
Clinician Investigator

Radiation Oncology
Los Angeles

Dr. Joan Ryoo is a radiation oncologist at the Kaiser Permanente Los Angeles Medical Center. Her research interests focus on the quality of cancer care in integrated health care systems, including the Veterans Health Administration and Kaiser Permanente. During her residency, she worked with the Department of Research & Evaluation to develop a natural language processing algorithm to identify patients with brain metastases who are not reliably captured in the tumor registry. This research ...

Featured Video

Research showing value of exercise before COVID-19 diagnosis earns special recognition

Being active can lower your risk of getting seriously ill with COVID, regardless of your race or the chronic conditions you may have, according to research published last year in the American Journal of Preventive Medicine.

The Kaiser Permanente Southern California findings were important, impactful, and influential. As a result, the journal editors chose the research article, “Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups,” as the American Journal of Preventive Medicine 2023 Article of the Year.

News

Featured Image of News Story Titled: Study examines outcomes of care at home for heart failure patients

Study examines outcomes of care at home for heart failure patients

For carefully selected patients, receiving advanced-level care at home after heart failure may be just as safe and effective as staying in the hospital, a new Kaiser Permanente Southern California study shows. The study, published on July 16, 2026, in JAMA Network Open, examined adults hospitalized for acute heart failure. Researchers compared patients who continued ...

Study finds lasting RSV vaccine protection for older adults

A respiratory syncytial virus vaccine given to older adults remained highly effective at preventing severe illness over 2 RSV seasons, according to a Kaiser Permanente Southern California study. The study offers real-world evidence that the bivalent RSVpreF vaccine continued to protect adults 60 and older from RSV-related hospitalizations and emergency department visits well beyond the ...

Clinical trial gives young pitcher a path back to baseball

When Chance Shipley was finishing high school in Southern California, baseball defined his future. A pitcher with a college scholarship, he was training for the transition to collegiate athletics when he became seriously ill during winter break in December 2019. He was vomiting, exhausted and noticed blood in his urine. At first, he said nothing. ...

Mpox study reveals hidden infections may fuel spread

A Kaiser Permanente study of nearly 8,000 men shows that in mid- to late 2024, mpox was far more common among men who have sex with men than previously thought. Individuals without symptoms accounted for most infections and likely played a prominent role in transmission, contrary to prior assumptions that people had to be symptomatic ...

DoxyPEP protects against some STIs, but effectiveness against gonorrhea diminishes

Taking doxycycline after sex helped prevent chlamydia and syphilis, but its ability to prevent gonorrhea faded over time as drug‑resistant strains became more common, according to new research. The findings show both the benefits and limits of a prevention strategy now widely used by patients, clinicians, and public health programs to prevent sexually transmitted infection ...

Featured Division

Clinician Research

The Division of Clinician Research provides support and resources for researchers who maintain clinical practices while building their own research portfolios. Key goals include fostering collaboration among clinician researchers, expanding research education, and promoting research that has the potential to transform care and improve the health of our communities.

The division, which was established in 2023, provides administrative support to the Regional Research Committee and the Clinician Investigator Program and manages a team of biostatisticians dedicated to physician research. It co-leads the Care Improvement Research Team, a group that brings together clinicians and research scientists to answer questions with the potential to change practice.

The division actively engages with various collaborators throughout the organization and is working to establish an interconnected network of clinicians, scientists, educators, administrators, and leaders who will work together to drive clinically impactful change through research.