As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Sujatha Murali is the principal investigator for breast cancer clinical trials within the Cancer Clinical Trials Access Program. She is a hematologist-oncologist at the San Marcos Medical Offices and San Diego Medical Center, also serving as the site principal investigator for all oncology clinical trials at those locations.
Dr. Murali has an extensive background in clinical research in breast cancer. She was a co-principal investigator in the breast cancer working group at Emory University ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
The updated national colorectal cancer screening guidelines that recommend screening begin at age 45 — rather than 50 — can benefit younger adults, a new Kaiser Permanente study found. The study was published October 22, 2024, in Annals of Internal Medicine. It included 267,732 Kaiser Permanente members in Northern California, Washington, and Colorado ages 45 ...
Breast cancer survivors commonly continue to use opioid pain killers after their cancer treatment is complete. A new Kaiser Permanente study shows that this can increase their risk of falls and bone fractures, lung problems, and cardiovascular conditions. The study was published in October 2024 in The Oncologist. A cancer epidemiologist partnered with a breast ...
Heidi Brown, MD, MAS, is a urogynecologist and a dissemination and implementation scientist who joined the Department of Research & Evaluation in August 2023. Her research focuses on improving access to effective solutions for pelvic floor disorders such as bladder and bowel incontinence and pelvic organ prolapse. She uses community engagement, user-centered design, and iterative ...
Monitoring of about 45,000 pregnant people receiving flu vaccines in each of 2 successive pregnancies showed no increased risk of side effects or health issues, according to a Kaiser Permanente study published September 19, 2024, in JAMA Network Open. “Our study’s findings support recommendations to give flu vaccinations to pregnant persons even if they received ...
A Kaiser Permanente Southern California study showed that 1 heart-failure medication worked best among the 3 most commonly used to prevent illness and disease among patients with chronic kidney disease and heart failure. “Beta blockers save lives in heart failure patients, but we wanted to see how this worked among patients who also had chronic ...
In our newest edition of IMPACT, we share stories of 2 recently released studies about flu vaccines. One looks at which vaccines are best for seniors, while the other assesses the safety of flu vaccines for women with closely spaced pregnancies. Another article examines research that found that gay men had shorter age-adjusted telomere length, which is a biomarker of aging, than straight men. Read also about research showing that beta blockers aren’t all the same for patients with heart failure and chronic kidney disease. The Q&A is with a researcher and physician who specializes in an often under-discussed issue: pelvic floor disorders. We wrap up with links to recent news articles on our research, including one in the New York Times.
Investigators with the Division of Health Services Research & Implementation Science study how care is delivered, identify opportunities for care improvement, and implement new approaches for organizing and delivering health services. The division brings together scientists with diverse expertise and training, including emergency medicine, epidemiology, health services research, implementation science, internal medicine, nursing, pharmaceutical economics, and pulmonology.
The division co-leads the Care Improvement Research Team, a research team embedded within Kaiser Permanente Southern California’s quality improvement ecosystem. The team works closely with clinical and operational partners at Kaiser Permanente Southern California to identify, prioritize, and solve problems related to quality and affordability. Its goal is to reduce unnecessary practice variation, improve affordability, and transform care.