As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Annette Regan is a pediatric and perinatal infectious disease epidemiologist in the Division of Epidemiologic Research. Her research focuses on maternal, pediatric, and adult vaccines.
Before joining Kaiser Permanente, she worked for federal and state health agencies including the Centers for Disease Control and Prevention and the state health department in Western Australia. Her research led to the development of novel vaccine safety surveillance systems for pregnant women and methods ...
Being active can lower your risk of getting seriously ill with COVID, regardless of your race or the chronic conditions you may have, according to research published last year in the American Journal of Preventive Medicine.
The Kaiser Permanente Southern California findings were important, impactful, and influential. As a result, the journal editors chose the research article, “Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups,” as the American Journal of Preventive Medicine 2023 Article of the Year.
Dr. Hui Zhou is the biostatistician lead in the Division of Epidemiologic Research for the Department of Research & Evaluation. There she collaborates with epidemiologists and clinical investigators on research studies ranging from conditions like hypertension, diabetes, chronic kidney disease, cardiovascular disease, and bone fractures. Dr. Zhou has extensive research experience in prediction model development ...
A Kaiser Permanente study found that the PREVENT cardiovascular risk equation had strong overall ability to predict 10-year cardiovascular disease risk in Asian, Native Hawaiian, and Other Pacific Islander adults. However, its accuracy differed across specific Asian ethnic subgroups and showed consistent patterns of over- and under-estimating when grouping by race and ethnicity. The study ...
For years, people living with relapsing forms of multiple sclerosis (MS) have depended on powerful medications to keep their disease under control. One of the most effective treatments has been rituximab, a therapy that works by depleting B cells, which are the immune cells that drive inflammation with MS. However, new research from Kaiser Permanente ...
For years, researchers have known that many people struggle to lose the weight they gain during pregnancy. Up to 1 in 4 individuals retain at least 10 pounds 1 to 2 years after giving birth, and this lingering weight can raise their long‑term risk of hypertension, cardiovascular disease, and other metabolic problems. Despite the importance ...
Wildfire smoke has increasingly been recognized as a serious public health threat. Now, 2 new Kaiser Permanente studies in Southern California have examined how health risks for both young and old people might be associated with exposure. One study showed that long-term exposure increased the risk of death among older adults, while another found that ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
Investigators with the Division of Biostatistics Research collaborate closely with scientists from the department’s other scientific divisions, as well as physician researchers at medical centers across Kaiser Permanente Southern California. They provide expertise and guidance on study design, power and sample size calculations, data management, data analysis and interpretation, and statistical methodology.
Investigators from the division have expertise in study design and data analysis for observational studies and clinical trials to address study questions. Their expertise spans standard and modern methods that deal with complex and big data for population and causal inferences as well as disease prediction.
Each division has at least one dedicated collaborative biostatistician research scientist assigned to provide statistical guidance on its research studies. In addition, one of the collaborative biostatistician researcher scientists leads the Regional Research Statistical Support team, which supports medical center-based researchers.