As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Matthew Mefford is a cardiovascular disease epidemiologist and research scientist in the Department of Research & Evaluation. His research interests focus on cardiovascular health including the study of risk factors, treatments, and cardiovascular outcomes, with an emphasis on the heart failure. He also maintains a broad focus on the prevention and treatment of hypertension, dyslipidemia, and diabetes for reducing cardiovascular disease risk.
Dr. Mefford has collaborated on cardiovascular ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
Taking doxycycline after sex helped prevent chlamydia and syphilis, but its ability to prevent gonorrhea faded over time as drug‑resistant strains became more common, according to new research. The findings show both the benefits and limits of a prevention strategy now widely used by patients, clinicians, and public health programs to prevent sexually transmitted infection ...
A large study conducted within Kaiser Permanente Southern California found that people with type 2 diabetes who primarily received diabetes self-management education and support were more likely to achieve healthy blood sugar levels than those whose care focused mainly on physician visits. “For people living with type 2 diabetes, this study shows that actively participating ...
This week, Nurses Week (May 6-12, 2026), we honor all the nurses who work within the Department of Research & Evaluation, who are a vital part of our research. Here we highlight Beatriz Alviso, RN, PHN, BSN who works in the Division of Health Services Research & Implementation Science. What is your background? I grew up ...
This week, Nurses Week (May 6-12, 2026), we honor all the nurses who work within the Department of Research & Evaluation, who are a vital part of our research. Here we highlight Christina Flores, LVN, who works in vaccine and infectious disease clinical trials. What is your background? I grew up in Highland Park, California, and ...
This week, Nurses Week (May 6-12, 2026), we honor all the nurses who work within the Department of Research & Evaluation, who are a vital part of our research. Here we highlight Sarah Ruiz, BSN, RN, PHN, who works in bone marrow transplant and pediatric clinical trials. What is your background? I grew up in Texas, ...
The latest IMPACT newsletter highlights Kaiser Permanente research and its real-world relevance. This issue explores why less frequent MS treatment may be just as effective, how staying active during pregnancy supports a healthier postpartum weight, and what new studies reveal about wildfire smoke risks. You’ll also find research on heart disease risk prediction across Asian ethnicities and a Q&A with Dr. Hui Zhou, reflecting on science, service, and being mom to this year’s Rose Queen.
Investigators with the Division of Biostatistics Research collaborate closely with scientists from the department’s other scientific divisions, as well as physician researchers at medical centers across Kaiser Permanente Southern California. They provide expertise and guidance on study design, power and sample size calculations, data management, data analysis and interpretation, and statistical methodology.
Investigators from the division have expertise in study design and data analysis for observational studies and clinical trials to address study questions. Their expertise spans standard and modern methods that deal with complex and big data for population and causal inferences as well as disease prediction.
Each division has at least one dedicated collaborative biostatistician research scientist assigned to provide statistical guidance on its research studies. In addition, one of the collaborative biostatistician researcher scientists leads the Regional Research Statistical Support team, which supports medical center-based researchers.