As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Annette Regan is a pediatric and perinatal infectious disease epidemiologist in the Division of Epidemiologic Research. Her research focuses on maternal, pediatric, and adult vaccines.
Before joining Kaiser Permanente, she worked for federal and state health agencies including the Centers for Disease Control and Prevention and the state health department in Western Australia. Her research led to the development of novel vaccine safety surveillance systems for pregnant women and methods ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
On a rainy New Year’s morning in Pasadena, Dr. Hui Zhou, a research scientist with the Department of Research & Evaluation, walked alongside Kaiser Permanente’s float, “A Better Idea for Health Care,” in the Rose Parade. It was a moment of pride and joy. Dr. Zhou wasn’t just proud to represent Kaiser Permanente. … ...
For many people, public parks are just a beautiful green space they drive by on their way to work. However, research has shown that parks play a crucial role in people’s physical activity, and the community’s health. By studying parks, researchers aim to understand how these public spaces enhance community health, encourage active lifestyles, and ...
Mingsum Lee, MD, PhD, has been named as the 2025 Southern California Permanente Medical Group Physician Researcher of the Year. Commenting about her selection for the award, one nominator said Dr. Lee “is a true quadruple threat as an exceptional clinician, educator, administrator, and prolific researcher, but also has a humility and generosity which defines ...
In January 2025, when wildfires swept from the foothills above Los Angeles into the densely populated urban areas below, evacuations ensued and a thick layer of smoke spread across the region. Air quality plummeted. The number of virtual visits soared and in-person visits also increased. Research led by Kaiser Permanente Southern California and the University ...
Researchers have developed a new risk calculation model to help predict the risks of heart problems for breast cancer survivors. Their research was published in JAMA Oncology in October 2025. “There is limited information about how breast cancer treatments can affect the development of cardiovascular disease,” said study co-senior author Reina Haque, PhD, MPH, a ...
Check out our latest issue for a roundup of our most recent research and profiles on a few of our newest postdocs. This issue features new findings on opioid tapering programs that show that patients on long-term high-dose opioids who gradually reduced their dose within 3 months faced a lower risk of overdose within a year. It also shares important recent findings that the COVID-19 vaccine does not increase the risk of tinnitus, as well as findings about patterns of breast cancer imaging and Type 2 diabetes remission.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.