About Our Program

As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.

Featured Scientist

Dr. John Sim headshot
John J. Sim, MD
Clinician Investigator

Nephrology and Hypertension
Los Angeles

Dr. John J. Sim is a nephrologist and clinical researcher at the Kaiser Permanente Los Angeles Medical Center. For over 13 years, Dr. Sim has studied the large, diverse membership of Kaiser Permanente Southern California by using electronic databases, disease registries, and pharmacy analytic information. His research focus is on population-based approaches to the treatment of chronic kidney disease, evaluation of the comorbidities and risk factors for CKD, and study of CKD-related outcomes such ...

Featured Video

Research showing value of exercise before COVID-19 diagnosis earns special recognition

Being active can lower your risk of getting seriously ill with COVID, regardless of your race or the chronic conditions you may have, according to research published last year in the American Journal of Preventive Medicine.

The Kaiser Permanente Southern California findings were important, impactful, and influential. As a result, the journal editors chose the research article, “Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups,” as the American Journal of Preventive Medicine 2023 Article of the Year.

News

Featured Image of News Story Titled: RSV vaccine protects older adults for at least 3 seasons

RSV vaccine protects older adults for at least 3 seasons

An RSV vaccine continued to protect adults aged 60 and older against RSV-related hospitalization and emergency department visits for at least 3 seasons after vaccination, according to a new study by Kaiser Permanente in Southern California. RSV, or respiratory syncytial virus, is a common respiratory virus that can cause serious illness, hospitalization, and even death ...

Five questions for Dr. Casey Luc

Casey Luc, PhD, MPH, an epidemiologist with expertise in HIV epidemiology in underserved communities, is the fifth Centers for Disease Control and Prevention Epidemic Intelligence Service officer to train with Kaiser Permanente Southern California’s Department of Research & Evaluation. Before joining Kaiser Permanente, he served as a health scientist contractor in the Syndemic Infectious Diseases ...

Five questions for Dr. Kevin Yu

Kevin Yu, PhD, is a postdoctoral research fellow in the Department of Research & Evaluation at Kaiser Permanente Southern California. He earned his PhD in health informatics from Northwestern University, where his work focused on pharmacoepidemiology and health informatics. His research focuses on cardiovascular disease and dementia, with a particular interest in target trial emulation ...

Weekly grocery deliveries help lower blood sugar

Managing Type 2 diabetes can be challenging. Food choices matter, but healthy options aren’t always easy to afford or find. A Kaiser Permanente study found that adults with diabetes who were on Medicaid improved their blood sugar when they received healthy grocery deliveries at home. ...

Study examines outcomes of care at home for heart failure patients

For carefully selected patients, receiving advanced-level care at home after heart failure may be just as safe and effective as staying in the hospital, a new Kaiser Permanente Southern California study shows. The study, published on July 16, 2026, in JAMA Network Open, examined adults hospitalized for acute heart failure. Researchers compared patients who continued ...

Featured Division

Biostatistics Research

Investigators with the Division of Biostatistics Research collaborate closely with scientists from the department’s other scientific divisions, as well as physician researchers at medical centers across Kaiser Permanente Southern California. They provide expertise and guidance on study design, power and sample size calculations, data management, data analysis and interpretation, and statistical methodology.

Investigators from the division have expertise in study design and data analysis for observational studies and clinical trials to address study questions. Their expertise spans standard and modern methods that deal with complex and big data for population and causal inferences as well as disease prediction. Each division has at least one dedicated collaborative biostatistician research scientist assigned to provide statistical guidance on its research studies.