As a research center embedded within Kaiser Permanente’s large and dynamic health care system, our investigators have a unique opportunity to apply scientific expertise to real-world clinical problems, translate findings into practice, and share what we learn with the broader community.
Dr. Anny Xiang is a senior research scientist and biostatistician and the director of Biostatistics Research for the Department of Research & Evaluation. Previously, she was an associate professor at the University of Southern California. She conducts collaborative and independent research. Dr. Xiang has a long track record of research on diabetes and gestational diabetes and has published many high-impact papers.
She is also a professor in the Department of Health Systems Science of ...
Over the years, clinical trials have led to amazing advances in treatment—even cures—for devastating illnesses. William Towner, MD, FACP, FIDSA, regional physician director for clinical trials, describes how trials at Kaiser Permanente contribute to the development of more effective and safer treatments for diseases such as HIV, hepatitis C, cancer, and more. (2:15)
The benefits of intensive blood pressure shown in the Systolic Blood Pressure Intervention Trial (SPRINT) also helps patients with chronic kidney disease, according to new research led by Kaiser Permanente and Stanford University. The study was published in January 2025 in JAMA Network Open. The SPRINT clinical trial included adults with hypertension and elevated cardiovascular ...
Young people who frequently used electronic media, such as computers, television, and social media, had less physical activity, more stress, and modest cognitive challenges. The study was published in January 2025 in Preventive Medicine. “Our research found an association between electronic media use and a negative impact on youth,” said the study’s lead author, Deborah ...
A recent Kaiser Permanente study described the incidence of IgA nephropathy, an autoimmune kidney disease, nationally, as well as among people of different race and ethnicities. The study was published in the American Journal of Nephrology in November 2024. “IgA nephropathy is a rare disease. Attempts to determine its incidence in the United States have ...
A new study by Kaiser Permanente has shown that the ABRYSVO respiratory syncytial virus vaccine is very effective in reducing emergency room visits and hospital stays due to RSV among older adults. “This Kaiser Permanente research demonstrated the real-world effectiveness of RSV vaccination among those 60 and over,” said lead author Sara Y. Tartof, PhD, ...
Exposure to a specific kind of air pollution, fine particulate matter, during pregnancy may significantly increase the risk of spontaneous preterm birth, which can be dangerous for both the mother and the baby, according to a Kaiser Permanente study published in JAMA Network Open. “Consistent with other study findings, this current study has demonstrated that ...
In our newest edition of IMPACT, we share some of our recent research including one study about the effectiveness of the side-effect monitor our researchers developed during the early days of COVID that has gone onto being used to get feedback on other vaccines. Another study examined issues with chronic kidney disease, and the story reveals how that research has gone onto change practice. Other stories focus on research into air pollution and the risk of preterm birth, younger adults and colon cancer screening outreach, opioid use among breast cancer survivors and the risk of falls, COVID vaccines, and heart failure. We’ve also got 2 Q&As, one with the 2024 physician researcher of the year and one with the director of our Division of Epidemiologic Research.
The Division of Clinical Trials Research advances medical innovation by supporting evaluation of new drugs, therapies, and devices to prevent and treat health problems. Our physician investigators work with cooperative groups and industry sponsors to conduct clinical trials for investigational drugs, biologics, and devices. In addition, the division develops pragmatic trials that help answer questions about care delivery.
The region has clinical trials programs in oncology (adult, gynecologic, pediatric, and surgical/radiation oncology), urology, gynecology, neurology, dermatology, metabolic diseases, nephrology, ophthalmology, infectious disease, cardiology, hepatology, vascular surgery, and rheumatology. Clinical trials staff support trials at medical centers and medical office buildings throughout the Kaiser Permanente Southern California Region.